A good sleep at night resets memory - Cornell University 

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Learning or experiencing new things activates neurons in the hippocampus, a region of the brain vital for memory. 

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During sleep, neurons repeat a pattern of activity, consolidating memories stored in the cortex.

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Deep sleep triggers a process in the hippocampus, where certain parts go silent, allowing neurons to reset and reuse the resources for new learning, next day.

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The brain resets memory by silencing specific neurons, particularly CA2, responsible for continuous learning without overloading, and resetting memory circuits.

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The hippocampus, divided into CA1, CA2, and CA3, encodes time and space memories, while CA2 generates silencing and resetting during sleep, according to a recent study.

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Researchers implanted electrodes in mice's hippocampi, enabling them to monitor neuronal activity during learning and sleep.

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During sleep, neurons in the CA1 and CA3 areas replicate the same neuronal patterns that developed during daytime learning.

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During experiment the active CA1 and CA3 regions experienced a sudden memory reset and got into quite state, generated by the middle region, CA2.

Researchers discovered that the brain has parallel circuits regulated by another two types of cells called--interneurons 

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The first type of interneurons is for memory regulation, and the other is for resetting memories.

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Researchers believe now they have tools to enhance memory, potentially useful in cases of memory impairment, such as Alzheimer's disease and post-traumatic stress disorder.

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Source: Cornell University  Researcher: Azahara Oliva  assistant professor (neurobiology)

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